Hardy–Weinberg allele frequencies: Class 12 practice
In a population in equilibrium, p + q = 1 and p² + 2pq + q² = 1, where p and q are allele frequencies and p², 2pq and q² are genotype frequencies. Read the method, follow the three worked examples, then try the six questions.
What you should know first
- Square roots
The idea behind hardy–weinberg allele frequencies
In a population in equilibrium, p + q = 1 and p² + 2pq + q² = 1, where p and q are allele frequencies and p², 2pq and q² are genotype frequencies. If the recessive phenotype frequency is known, q = √(q²).
Step-by-step method
- Find q² from the recessive phenotype.
- q = √q², p = 1 − q.
- Carriers = 2pq.
Worked example 1 (Basic)
In a population, q = 0.3. Find p and the frequency of heterozygotes.
- p = 1 − 0.3 = 0.7
- 2pq = 0.42
- Answer: p = 0.7, 2pq = 0.42
Worked example 2 (Standard)
4% of a population show a recessive trait. What percentage are carriers?
- q² = 0.04 → q = 0.2
- p = 0.8; 2pq = 0.32
- Answer: 32%
Worked example 3 (Challenge)
In 10000 people, 225 have a recessive condition. Estimate how many are homozygous dominant.
- q² = 0.022, q = 0.15, p = 0.85
- p²N = 7225
- Answer: 7225
Common mistakes and misconceptions
- Using q² as q
- Forgetting the 2 in 2pq
Practice questions
- (Basic) In a population, q = 0.2. Find p and the frequency of heterozygotes.
- (Basic) In a population, q = 0.4. Find p and the frequency of heterozygotes.
- (Standard) 6.25% of a population show a recessive trait. What percentage are carriers?
- (Standard) 1% of a population show a recessive trait. What percentage are carriers?
- (Challenge) In 2000 people, 5 have a recessive condition. Estimate how many are homozygous dominant.
- (Challenge) In 10000 people, 25 have a recessive condition. Estimate how many are homozygous dominant.
Answer key with full working
- Q1: p = 1 − 0.2 = 0.8 → 2pq = 0.32 → Answer: p = 0.8, 2pq = 0.32
- Q2: p = 1 − 0.4 = 0.6 → 2pq = 0.48 → Answer: p = 0.6, 2pq = 0.48
- Q3: q² = 0.063 → q = 0.25 → p = 0.75; 2pq = 0.375 → Answer: 37.5%
- Q4: q² = 0.01 → q = 0.1 → p = 0.9; 2pq = 0.18 → Answer: 18%
- Q5: q² = 0.003, q = 0.05, p = 0.95 → p²N = 1805 → Answer: 1805
- Q6: q² = 0.003, q = 0.05, p = 0.95 → p²N = 9025 → Answer: 9025
Syllabus note
This skill is listed under "Evolution" for Class 12 in the NCERT/CBSE books. ICSE, IGCSE, IB and state boards may teach it in a different chapter or year.
Answers on this page are generated and automatically re-checked by a second, independent calculation. They have not been reviewed by a teacher — if you spot a problem, tell us on WhatsApp.
Related practice and notes
Frequently asked questions
Which chapter is hardy–weinberg allele frequencies in?
"Evolution", Class 12 Biology (NCERT/CBSE). Other boards may place it differently.
How were the answers checked?
Answers on this page are generated and automatically re-checked by a second, independent calculation. They have not been reviewed by a teacher — if you spot a problem, tell us on WhatsApp.